Confirming the validity and responsiveness of the multiple. The 12 item ms walking scale msws12 measures walking ability by assessing the impact of ms on 12 aspects of walking function and quality walking, running, climbing stairs, standing, balance. Each completed the selfreported 12item multiple sclerosis walking scale msws12,6 msss88,2 and barthel index questionnaires,7 alongside the clinicianrated ashworth scale as,8 and a laboratorybased measure of ankle spasticity. Multiple sclerosis ms is a demyelinating disease of the central nervous system characterized by episodic decline in various neurologic functions. The multiple sclerosis walking scale msws12 assesses the impact of ms on walking ability from the patients perspective, but in its current form, is not amenable for use in many policy decision making settings. The multiple sclerosis walking scale is a selfassessment scale which measures the impact of ms on walking. Multiple sclerosis quality of life msqol54 instrument.
In a version 2, three items are scored, and nine items are. This study examined the validity of those mcid values based on capturing corresponding changes in other walking outcomes in persons with multiple sclerosis ms. The scale has not been independently validated for use in differing ms populations. The msws12 is a 12item pro of the impact of ms on walking. Doctor discussion guide talking about walking ampyra. Mapping the 12item multiple sclerosis walking scale to.
Profiling walking dysfunction in multiple sclerosis. The t25fw is a clinical tool that evaluates patients for quantitative mobility and leg function performance test in a timed, 25 foot walk. The msw12 questionnaire is designed to measure how multiple sclerosis has affected the individuals walking ability. It consists of 12 questions concerning the limitations to walking due to ms during the past 2 weeks. Subjects also completed two selfreport assessment questionnaires. Evaluation of the multiple sclerosis spasticity scale 88. Multiple sclerosis walking scale12 and oxygen cost of. The psychometric properties of the msws12 were excellent, and in. This study aimed to describe the selfperceived walking limitations of those with multiple sclerosis ms using the swedish translation of the 12item ms walking scale msws12 s, and to investigate it for concurrent validity and internal consistency. The time is calculated from the initiation of the patient instructed to begin, until the patient has.
Multiple sclerosis outcome measures taskforce compendium of. Mapping the 12item multiple sclerosis walking scale to the. The 12item multiple sclerosis walking scale msws 12 is a patientreported outcome measure that assesses patients perception of the impact of multiple sclerosis ms on walking ability, but cannot be used in costeffectiveness or costutility analyses which require a healthutility score to calculate qualityadjusted lifeyears. This study aimed to profile gait pathology in gaitimpaired patients with ms using comprehensive 3d. We sought to evaluate the effect of dalfampridineer tablets prolongedrelease fampridine in europe on health utility in patients with multiple sclerosis ms by mapping subjects individual item scores from the 12item multiple sclerosis walking scale msws12 onto the euroqol. The ms walking scale msws12 has the obvious limitation of focusing only on walking 10, 11. Further validation of multiple sclerosis walking scale12 scores. The exercise group participated in a programme of 12 supervised 30min sessions of balance exercises using wii games, twice a week for 67 weeks. Activitiesspecific balance confidence in people with. One hundred fortynine patients in the community and 53 hospital outpatients with ms completed the msws 12 and other outcome measures. The 12 item ms walking scale msws 12 measures walking ability by assessing the impact of ms on 12 aspects of walking function and quality walking, running, climbing stairs, standing, balance. Mapping of multiple sclerosis walking scale msws12 to.
The most challenging activities were standing on a chair and reaching for something, stepping onto or o. Casp12 definition the original casp19 scale hyde et al. Estimation of the effect of dalfampridineer on health. The patient is directed to walk 25 feet quickly and safely as possible from one marked end to the other. Validity of minimal clinically important difference values. Mapping from the multiple sclerosis walking scale msws12. Twelve item ms walking scale msws12 sailing sclerosis. An equation for mapping the msws12 to the eq5d was previously developed and validated using a north american research committee on.
The multiple sclerosis walking scale12 msws12 is a multiitem rating scale used to assess the perspectives of patients about the impact of ms on their walking ability. Gait dysfunction is a common and relevant symptom in multiple sclerosis ms. The 12item multiple sclerosis walking scale msws 12 is a patientreported outcome that assesses the impact of walking impairment in people with ms. The most recent and best validated of these is the 12item multiple sclerosis walking scale msws12.
The msws12 is a patientrated measure of the impact of ms on walking that was developed using standard methods of test construction and validated in community and hospitalresiding samples of individuals with ms 2. Multiple sclerosis ms is a chronic neuroinflammatory and neurodegenerative disorder of the central nervous system. Crosscultural adaptation and validation of the 12item. A multicentre, randomised, controlled singleblinded trial with random allocation to exercise or no exercise. A conversation with your doctor about walking difficulty might be an important first step. An equation for mapping the msws12 to the eq5d was previously developed and validated using a north american research committee on ms narcoms registry cohort.
Twelve item ms walking scale msws 12 graph patient progress over time twelve item ms walking scale use the graphs below to plot the percentage score from the questionnaire at each visit. The 12item ms walking scale msws12 assesses patients measurement. Mapping of multiple sclerosis walking scale msws12 to five. Eightyone persons, recruited from five centres in sweden, were tested using the four square step test fsst, the timed up and go cognitive. The 12item multiple sclerosis walking scale msws 12 is a selfreport measure of the impact of ms on the individuals walking ability. Vickrey, md, mph ucla department of neurology c128 rnrc. The north american research committee on multiple sclerosis narcoms patient registry has developed validated performance scales ps 12, in areas including walking, fatigue, cognition, and. Instrumented balance and walking assessments in persons. One hundred fortynine patients in the community and 53 hospital outpatients with ms completed the msws12 and other outcome measures. Higher scores indicate a greater impact on walking than lower scores. Mapping the 12item multiple sclerosis walking scale to the euroqol. The 12item multiple sclerosis walking scale msws12 is a patientreported outcome that assesses the impact of walking impairment in. The multiple sclerosis walking scale msws12 is the predominant patientreported measure of multiple sclerosis ms elated walking ability, yet it had not been analyzed using item response theory irt, the emerging standard for patientreported outcome pro validation. The 12 item multiple sclerosis walking scale msws 12 is a new, selfrated measure of walking ability.
Example items are in the past two weeks, how much has ms limited your ability to walk. Gait dysfunction in ms is distinguished by decreased gait speed, walking endurance, step length, cadence and joint motion, as well as increased metabolic cost of walking and increased variability of gait. Trials have not assessed the effect of dalfampridineextended release dalfampridineer on health utility. Multiple sclerosis walking scale 12 items eeducation eurims. A change will be indicated by a reduction or increase. Request pdf measuring the impact of ms on walking ability. Full text mapping of multiple sclerosis walking scale. Balance exercise for persons with multiple sclerosis using. While the msws12 is increasingly being used in clinical trials, observational studies, and clinical practice, it lacks the ability to measure health. The multiple sclerosis rating scale, revised msrsr. Both the abc and the 12item ms walking scale are selfrating scales and incorporate standing and walking activities though the 12item ms walking scale is focused on limitations. Minimal clinically important difference mcid values of 4 and 6 points have been proposed for interpreting meaningful change in multiple sclerosis walking scale12 msws12 scores. The 12item multiple sclerosis walking scale msws12 is a patientreported outcome measure that assesses patients perception of the impact of ms on walking ability. Italian validation of the 12item multiple sclerosis walking scale.
For each statement, please circle the one number that best describes your degree of limitation. The 12item ms walking scale msws12 assesses patients measurement of walking quality. The psychometric properties of the msws 12 were excellent, and in. The original scoring provides options 15 for each item, with 1 meaning no limitation and 5 meaning extreme limitation on the gaitrelated item. The 12item multiple sclerosis walking scale msws12 is a selfreport measure of the impact of ms on the individuals walking ability. To develop a patientbased measure of walking ability in ms. The scale is composed of four subscales, the initials of which make up the acronym. Gait impairment is commonly in people with multiple sclerosis ms. Preliminary psychometric evaluation data quality, scaling assumptions, acceptability, reliability, validity was undertaken in the data. Validation of patient determined disease steps pdds.
Progressive ms is defined by the gradual accumulation of neurological disability independent of relapses, typically with lack of or. Measuring the impact of ms on walking ability neurology. Each item can be answered with 5 options, with 1 meaning no limitation and 5 extreme limitation. Italian validation of the 12item multiple sclerosis. While the msws 12 is increasingly being used in clinical trials, observational studies, and clinical practice, it lacks the ability to measure health. The 12item multiple sclerosis walking scale msws12 is a new, selfrated measure of walking ability.
Msws12 scores are generated by summing the scores from all items, subtracting the minimum score 12, dividing by the maximum score 48, and then. Marangoni1, karina pavan2, charles peter tilbery3 multiple sclerosis ms is an autoimmune disease of the. The 12item ms walking scale msws12 is a patientreported measure that was developed to facilitate assessment of the impact of ms on walking impairment from the patients perspective. The 12item multiple sclerosis walking scale msws12 is a selfreport. Rating scales for neurologists journal of neurology.
The higher the scorepercentage, the greater the perceived impact ms is having on walking ability. The first 12 questions of this guide are based on the 12item multiple sclerosis walking scale msws12a validated, selfreported patient questionnaire rating the effect of ms on walking. The 12item multiple sclerosis walking scale msws 12 what does this author special investigating alternative medicine but in many cases most patients to ever be truly better improving the patient has been brought on by facial movements through even with associated with. Hobart jc, riazi a, lamping dl, fitzpatrick r, thompson aj. Multiple sclerosis quality of life msqol54 instrument for further information, contact. Multiple sclerosis impact scale msis29 the following questions ask for your views about the impact of ms on your daytoday life during the past two weeks for each statement, please circle the one number that best describes your situation please answer all questions in the past two weeks. The aim of this study was to crossculturally adapt and validate the msws12 for the italian population with ms. The aim of this study was to examine the reliability and validity of the msws12 in persian speaking patients with ms. The 12 item ms walking scale msws 12 is a patientreported measure that was developed to facilitate assessment of the impact of ms on walking impairment from the patients perspective. Perceptions of limitations in walking and balance confidence were closely related. Gait impairment is reported by 85% of patients with multiple sclerosis ms as main complaint. Six ms outpatient clinics across italy enrolled subjects between june 20 and december 20. Dichotomised msws12 item scores and participant age and gender model g.